Factors such as age at menopause and a woman’s breast-feeding practices can influence her risk of developing certain types of breast cancer. That was the conclusion of a new study to be published in the October 1, 2008, issue of CANCER. The study’s results suggest that there are distinct and separate hormonal risk factors associated with different subtypes of breast cancer. More>>

Measuring a woman’s bone mineral density (BMD) can provide additional information that may help to more accurately determine a woman’s risk of developing breast cancer, according to a new study in the journal Cancer. More>>

Measuring a woman's bone mineral density can provide additional information that may help to more accurately determine a woman's risk of developing breast cancer. That is the conclusion of a new study to be published in the September 1, 2008, issue of CANCER. More>>

Mastectomy rates have been on the upswing at the Mayo Clinic in Rochester, Minnesota, and researchers cited MRI as a factor influencing the increase. More>>

Anthracyclines have been a cornerstone in the adjuvant treatment of breast cancer for more than 25 years and have well-established risks and benefits. But new molecular assays may make it possible to predict which women will benefit from this therapy, and new agents may offer better alternatives. More>>

Positive data were reported from the first-ever randomized, multicenter, open-label phase III trial of the combination of two targeted agents, lapatinib (Tykerb) and trastuzumab (Herceptin), in women with HER2-positive metastatic breast cancer. The study results, which were presented at the annual ASCO meeting in Chicago, demonstrated a benefit from the combination (abstract 1015). More>>

CHICAGO—In recurrent or metastatic breast cancer, the addition of bevacizumab (Avastin) significantly improved progression-free survival over treatment with docetaxel (Taxotere) alone, European investigators reported at ASCO 2008 (abstract LBA-1011). More>>

The patient, EC, is a premenopausal 38-year-old mother of four school-age children. Her mother had been diagnosed and treated for breast cancer. Because of her family history of breast cancer, EC had her first mammogram at age 36. That first mammogram showed clustered calcifications and EC was told this was a warning sign. A biopsy was negative for cancer. In spite of the reassuring report, EC opted to return every 6 months for follow-up with her obstetrician-gynecologist. More>>

Breast Cancer is a unique effort in the world of breast cancer texts: Compact and concise, this 214-page book deals exclusively with breast cancer therapeutics, and strives to accomplish the difficult task of being as current as possible within the limited capabilities of the printed word in a rapidly evolving field. Dr. Seidman has assembled a distinguished group of authors, each of whom was assigned a topic, in the end covering all aspects of the medical oncologic scope of breast cancer... More>>

The Cancer International Research Group (CIRG), a division of TRIO (Translational Research in Oncology) announced that, based on its study BCIRG 006, the US Food and Drug Administration (FDA) has approved a new regimen known as TCH (docetaxel [Taxotere] and carboplatin combined with trastuzumab [Herceptin]) for the adjuvant treatment of HER2-positive early breast cancer. The AC-TH regimen (doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab), also investigated in the BCIRG 006... More>>