Articles by Daniela Freitas, MD

Perioperative Treatment of Gastrointestinal Stromal Tumors
ByGustavo Dos Santos Fernandes, MD,Charles D. Blanke, MD, FACP,Daniela Freitas, MD,Rodrigo Guedes, MD,Paulo M. Hoff, MD, FACP Gastrointestinal stromal tumors (GISTs) originate from the interstitial cells of Cajal or a precursor and are the most common mesenchymal neoplasms of the gastrointestinal (GI) tract.[1] Although GISTs often present as localized masses, they are typified by a high risk of metastatic relapse, most commonly in the liver and peritoneum.

Adjuvant therapy is defined as any treatment administered after surgical resection of a primary tumor with the intent of improving the patient’s outcome by eliminating any occult, viable tumor cells that may have remained after surgery.