Adjuvant Treatment of Stage IB NSCLC: The Problem of Stage Subset Heterogeneity
April 30th 2008Stage IB non–small-cell lung carcinoma (NSCLC) represents a subset of early-stage, resectable NSCLC, usually treated with curative intent, but with historically modest 5-year survival rates ranging from 40% to 67% with surgical resection alone.[1,2] Disappointingly, modern adjuvant chemotherapy trials including stage IB patients have shown little evidence of chemotherapeutic benefit.
Evolution of Combined Modality Therapy for Stage III Non–Small-Cell Lung Cancer
A number of randomized clinical trials and meta-analyses now support the conclusion that combined modality regimens that include cisplatin (Platinol)-based chemotherapy improve survival in stage III non–small-cell lung
Gemcitabine/Carboplatin Combination Regimens: Importance of Dose Schedule
July 1st 2000Platinum compounds, either cisplatin (Platinol) or carboplatin (Paraplatin), in combination with a number of new chemotherapeutic agents, have demonstrated improved response or survival compared to cisplatin alone or older