John Skibber, MD

Articles

Preoperative UFT/Leucovorin and Radiation Therapy in Rectal Cancer

Paulo M. Hoff, MD, FACP;Everardo D. Saad, MD;Nora Janjan, MD, MPSA, MBA;John Skibber, MD;Richard Pazdur, MD

October 1st 2000

The use of combined modality regimens has been well established in the treatment of stages II and III rectal cancer. The most common chemotherapy regimens used include continuous-infusion 5-FU delivered with the help of a central venous catheter and the use of portable pumps.

Preoperative UFT and Calcium Folinate and Radiotherapy in Rectal Cancer

Paulo M. Hoff, MD, FACP;Richard Pazdur, MD;Nora Janjan, MD, MPSA, MBA;Christopher H. Crane, MD;John Skibber, MD

July 1st 1999

Protracted infusions of 5-fluorouracil (5-FU) combined with pelvic radiotherapy have been associated with improved survival and decreased local and distant metastases in the adjuvant therapy of rectal cancer. However,