Maryann Redlinger, RN
Articles
Irinotecan and UFT/Leucovorin in Patients With Advanced Cancers
James P. Stevenson, MD;Maryann Redlinger, RN;Weijing Sun, MD, FACP;Daniel G. Haller, MD;Peter J. O'dwyer, MD
October 1st 2000The combination of irinotecan and fluorouracil (5-FU) is synergistic when applied to human colon cancer cell lines in vitro and appears to be schedule-dependent: maximal activity occurs when irinotecan is administered prior to 5-FU. In this phase I study, irinotecan is administered in combination with UFT and leucovorin in patients with advanced solid tumors.
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