CRC: Clinical Trial Landscape for MRD-Based Early Intervention
An overview colorectal cancer clinical trials studying early intervention based on MRD positivity.
Relapsed/Refractory Multiple Myeloma: Practice Pearls and Future Directions in Care
Thomas Martin, MD; Ajay Nooka, MD; and Jeremy Larsen, MD, share closing thoughts on the evolving landscape of cytokine release syndrome management in relapsed/refractory multiple myeloma.
‘Unprecedented’ Results Support Dostarlimab Approval in Endometrial Cancer
Dostarlimab plus chemotherapy produces notable benefits among patients with advanced, mismatch repair deficient endometrial cancer in the phase 3 RUBY trial.
Novel Therapies May Lead to More Treatment Options in Sarcoma Subtypes
CAR T-cell therapies and immunotherapy agents may offer up new options and even become standard of care in certain sarcoma subtypes.
Relapsed/Refractory Multiple Myeloma: An Evolving Treatment Landscape
Closing out their program on relapsed/refractory multiple myeloma, Ajai Chari, MD, and Carolina Schinke, MD, consider optimal treatment strategies in the current landscape and look toward future directions in care.
Indirect Comparison of Acalabrutinib Versus Zanubrutinib in RR CLL: Efficacy Analysis
Alan Skarbnik, MD, and Ryan Jacobs, MD, review efficacy data from the indirect comparison study of acalabrutinib versus zanubrutinib in relapsed/refractory chronic lymphocytic leukemia.
The AML Treatment Horizon
Experts on acute myeloid leukemia offer closing thoughts and discuss emerging treatments in the field.
Determining Which Patients Will Benefit the Most From Menin Inhibitor Treatment
The expert panel provide clinical insights on which patients with AML may benefit the most from treatment with menin inhibitors.
The Role of Menin Inhibitors in the AML Treatment Armamentarium
The panel of experts share their thoughts on where menin inhibitors will offer the most benefit in the overall treatment regimen for patients with AML.
Clinical Trials With BTK Inhibitors in Relapsed/Refractory CLL
Focused discussion on key clinical trial data behind currently available BTK inhibitors for patients with relapsed/refractory chronic lymphocytic leukemia.
Emerging Advancements in the Treatment of Clear Cell RCC
The panel highlights novel agents under investigation for the treatment of clear cell renal cell carcinoma.
Expert Reviews Novel Treatment Options Across Sarcoma Subtypes
There are several novel treatments that may be beneficial in several sarcoma subtypes including CAR T-cell therapies and immune checkpoint inhibitors, according to Sandra P. D’Angelo, MD.
Atezolizumab Plus Cabozantinib Versus Cabozantinib Monotherapy for Metastatic RCC
Moshe Ornstein, MD, reviews the design and efficacy and safety data from the phase 3 CONTACT-03 study in metastatic renal cell carcinoma.
Communication is ‘Paramount’ in Managing Chemotherapy Shortage
Recommendations penned by the American Society of Clinical Oncology and Society for Gynecologic Oncology may be critical in managing the ongoing chemotherapy shortage, according to Michael Ganio, PharmD, MS, BCPS, FASHP.
Bladder Cancer: Educating Patients on Treatment Schedules and Adverse Events
Genitourinary cancer experts share insight on best practices in educating patients on treatment schedules and adverse events when receiving therapy for advanced bladder cancer.
Bladder Cancer Management: Best Practices in Radiation Therapy
Focused discussion on the optimal use of radiation therapy strategies, alone or in combination with systemic therapy, for patients with advanced bladder cancer.
Patient Case Introduction: 66-year-old Male Diagnosed with R/R MM
Subject matter experts share strategies for determining treatment selection and duration for patients with transplant-ineligible NDMM.
Clinical Insights Concerning the Management of Patients with NDMM
Evolving Management of EGFR Exon20+ NSCLC: Future Directions in Care
Closing out their discussion on EGFR Exon20+ non–small cell lung cancer, Joshua Sabari, MD, and Misako Nagasaka, MD, share excitement for future evolutions in the treatment paradigm.
Advanced NSCLC: CNS Penetration With Novel EGFR TKI Therapy
A brief review of novel EGFR TKIs that may have stronger CNS penetration in patients with non–small cell lung cancer and brain metastases.