Clinical study of ctDNA-based MRD detection and INTERCEPT program update

Opinion
Video

The panel examines recent studies from the INTERCEPT program investigating the utility of circulating tumor DNA (ctDNA) for minimal residual disease (MRD) detection in colorectal cancer (CRC).

  1. Please describe some recent studies exploring the utility of ctDNA in CRC
  2. Dr Dasari: INTERCEPT program: ctDNA testing for MRD in CRC
  3. Association of positive ctDNA-based MRD assays during surveillance and undiagnosed concomitant radiographic recurrences CRC (Dasari, et al. ASCO 2023. Abstract 3522.)
  4. Results from a prospective real-world clinical cohort (Maddalena, et al. ASCO GI 2024. Abstract 27.)

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