Following recent data from the ADRIATIC study, the Oncology Brothers and Eric Singhi, MD, discuss the role of prophylactic cranial irradiation (PCI) in patients with small cell lung cancer.
DLL3-Targeted ADC Produces Responses in Previously Treated ES-SCLC
Promising phase 1 data appear to support further evaluation of ZL-1310 as a treatment for patients with extensive-stage small cell lung cancer.
Updated ASCO Guidelines for Optimal Small Cell Lung Cancer Management
Practices are on the cusp of better understanding small cell lung cancer that in turn can help to advance treatment strategies for patients, says Gregory Peter Kalemkerian, MD.
Lurbinectedin Combo Yields Significant OS/PFS in ES-SCLC
Developers plan to submit a supplemental NDA for this combination as a first-line maintenance therapy for ES-SCLC in the first half of 2025.
Oncology Peer Review On-The-Go: Future Directions in Small Cell Lung Cancer Treatment
In the final part of the small cell lung cancer podcast series, CancerNetwork® and Wade Iams, MD, discuss the future of treating patients with this disease.
Concurrent Chemoradiation/Atezolizumab Does Not Improve Survival in LS-SCLC
Data show that twice-daily radiotherapy may confer improved survival vs once-daily radiation in patients with limited-stage small cell lung cancer.
Novel Monoclonal Antibody Combo Shows Modest PFS Benefit in Extensive-Stage SCLC
BMS-986012 in combination with nivolumab/chemotherapy showed numerical PFS improvements in those with and without brain metastases at baseline.