Key Highlights From the PERSEUS and CASSIOPEIA Studies

Opinion
Video

Panelists discuss how recent pivotal trials like PERSEUS and CASSIOPEIA demonstrate superior outcomes with daratumumab-based quadruplet and triplet combinations compared with standard regimens in transplant-eligible newly diagnosed multiple myeloma patients, particularly showing improved progression-free survival when daratumumab is added to VRd (bortezomib, lenalidomide, and dexamethasone) or VTd (bortezomib, thalidomide, and dexamethasone) backbones.

Video content above is prompted by the following:

  • Let’s begin our discussion with newly diagnosed multiple myeloma, specifically in patients who are transplant eligible. Can you briefly comment on recent updates surrounding combination therapies for transplant-eligible NDMM:
  • Dara-VRd vs VRd
  • Dara-VTd vs VTd
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