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|Articles|December 1, 2007

Oncology NEWS International

  • Oncology NEWS International Vol 16 No 12
  • Volume 16
  • Issue 12

Novacea halts ASCENT-2 trial

Novacea halts ASCENT-2 trial

SOUTH SAN FRANCISCO, California—Novacea, Inc has ended its phase III ASCENT-2 clinical trial of Asentar (DN-101), the company's investigational cancer therapy for the treatment of androgen-independent prostate cancer. The trial was halted due to an imbalance of deaths between the two treatment arms, as observed by the study's Data Safety Monitoring Board. The study was comparing the benefits of weekly Asentar, an oral, intermittent high dose of calcitriol, plus docetaxel (Taxotere) with the current standard of care. The company plans to fully analyze the data to attempt to understand the cause of the higher death rate in the Asentar/Taxotere treatment group.

Articles in this issue

over 18 years ago

Third-line single-agent cetuximab ups overall survival

over 18 years ago

Modern multislice CT propels pancreas imaging forward

over 18 years ago

Sorafenib gets ok for liver cancer

over 18 years ago

Celgene to acquire Pharmion

over 18 years ago

RT/temozolomide raises possibility of cure in glioblastoma

over 18 years ago

Brachytherapy as effective in younger as in older men

over 18 years ago

MMA not harming patients

over 18 years ago

Kinase inhibitor may prevent RT-induced lung injury

over 18 years ago

FDA approves lower starting dose for dasatinib for CML

over 18 years ago

Encouraging Avastin results in glioblastoma multiforme

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