Penn Study Examines Power of Exercise to Prevent Breast Cancer

A new federally funded University of Pennsylvania School of Medicine study aims to learn whether women at high risk of breast cancer can use exercise to meaningfully reduce their risk of getting the disease. Building on evidence that reducing estrogen in the body reduces cancer risk, and that elite female athletes experience a drop in estrogen levels that often cause them to stop ovulating and menstruating, the Women in Steady Exercise Research (WISER) Sister trial will investigate two different levels of regular treadmill exercise as a possible intervention for breast cancer risk reduction. The investigators plan to use their findings to offer effective exercise guidelines for high-risk women.