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Home to the journal Oncology, Cancer Network provides research and opinion on the screening, early detection, diagnosis, treatment, and prevention of cancers.

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Treatment Sequencing Strategies in R/R Multiple Myeloma

Video Series

Pooled Analysis from MagnetisMM Studies

Videos

A panel of experts on relapsed/refractory multiple myeloma review clinical trial data on novel therapies and drug combinations and discuss treatment decision-making and sequencing practices.

A panel of myeloma specialists review the case of a 67-year-old patient with multiple myeloma (MM) who received a bispecific antibody.

Clinical Scenario 1: A 67-Year-Old Man with Multiple Myeloma

Following the presentation of a case of a patient with multiple myeloma, the panel have a roundtable discussion on how to approach treatment. 

Treatment Options in Late-line R/R MM Patients

Focusing on treatment paradigms for patients with relapsed/refractory multiple myeloma, the expert panel discusses the role of BCMA-targeted bispecifics and how they might consider sequencing therapies.

Sequencing Options of Bispecifics in R/R MM

Thomas G. Martin, MD, reviews findings from a pooled analysis from MagnetisMM that evaluated elranatamab in patients with relapsed/refractory MM who received prior BCMA-directed therapies.

The panel discusses how they approach treatment selection and sequencing for patients with relapsed/refractory multiple myeloma.

Consideration in Treatment Selection and Sequencing in R/R MM

Shaji Kumar, MD, presents the case of a 70-year-old patient with relapsed/refractory multiple myeloma who received CAR T-cell therapy.

Clinical Scenario 2: A 70-Year-Old Male with R/R MM

Following the presentation of a case of a patient with relapsed/refractory multiple myeloma, the expert panel reviews treatment options.

Treatment Options for Late-line R/R MM

Shaji Kumar, MD, reviews data from cohort C of CARTITUDE-2 and a real-world study evaluating ide-cel in patients with relapsed/refractory multiple myeloma.

Overview of CAR-T Sequencing Strategies in R/R MM

Experts on multiple myeloma outline current challenges in determining the optimal treatment strategy for patients with relapsed/refractory disease who are eligible for bispecifics and CAR T-cell therapy.

Challenges in Optimizing Sequencing

Future Clinical Trials: Sequencing Decisions for Bispecifics and CAR T-Cell Therapy

Challenges in Optimizing Sequencing Strategies in R/R MM

The panel concludes its discussion with key takeaways on unmet needs and evolving treatment paradigms in relapsed/refractory multiple myeloma.

Unmet Needs and Future Perspectives in Treatment Sequencing Strategies in R/R MM

Pooled Analysis from MagnetisMM Studies

EP: 1.Clinical Scenario 1: A 67-Year-Old Man with Multiple Myeloma

EP: 2.Treatment Options in Late-line R/R MM Patients

EP: 3.Sequencing Options of Bispecifics in R/R MM

EP: 4.Pooled Analysis from MagnetisMM Studies

EP: 5.Consideration in Treatment Selection and Sequencing in R/R MM

EP: 6.Clinical Scenario 2: A 70-Year-Old Male with R/R MM

EP: 7.Treatment Options for Late-line R/R MM

EP: 8.Overview of CAR-T Sequencing Strategies in R/R MM

EP: 9.Challenges in Optimizing Sequencing

EP: 10.Future Clinical Trials: Sequencing Decisions for Bispecifics and CAR T-Cell Therapy

EP: 11.Challenges in Optimizing Sequencing Strategies in R/R MM

EP: 12.Unmet Needs and Future Perspectives in Treatment Sequencing Strategies in R/R MM

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