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|Articles|October 1, 2007

Oncology NEWS International

  • Oncology NEWS International Vol 16 No 10
  • Volume 16
  • Issue 10

Taxotere combination approved for induction therapy in SCCHN

FDA has approved Sanofi-Aventis' Taxotere (docetaxel) for use in combination with cisplatin and fluorouracil (TPF) for the induction treatment of patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN)

ROCKVILLE, Maryland—FDA has approved Sanofi-Aventis' Taxotere (docetaxel) for use in combination with cisplatin and fluorouracil (TPF) for the induction treatment of patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN).

FDA based its approval on TAX- 324, a multicenter, open-label, randomized trial of 501 patients. Overall survival was significantly prolonged with the Taxotere-containing regimen, compared with PF alone (P = .0058). Median survival was 70.6 months in the TPF group vs 30.1 months in the PF group (HR 0.70).

Articles in this issue

over 18 years ago

BRCA1 overexpression is strongly linked to poor outcome in NSCLC patients treated with cisplatin

over 18 years ago

Bill aims to 'revitalize' FDA by adding powers and databases

over 18 years ago

New myeloma trial results; two new studies initiated

over 18 years ago

Neoadjuvant trastuzumab increases pCR rates

over 18 years ago

Court rejects right of terminally ill to unproven drugs

over 18 years ago

Sorafenib improves overall survival in Asian HCC pts

over 18 years ago

Skipping tam doses increases risk of death

over 18 years ago

The SGR: The madness behind physician payment fee cuts

over 18 years ago

Dr. Pegram seeks new breast cancer challenges at Miami

over 18 years ago

SearchMedica.com receives award

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