Management of Brain Metastases in the Era of Targeted and Immunomodulatory Therapies
April 15th 2015Some targeted systemic therapies have demonstrated evidence of activity in the brain-specifically in melanoma, lung cancers, and breast cancers-and these agents warrant further study in clinical trials.
Tailored Therapy in Diffuse Gliomas: Using Molecular Classifiers to Optimize Clinical Management
June 15th 2013We review the current data regarding the prognostic and predictive value of IDH mutation and 1p/19q codeletion in gliomas. We also discuss possible management algorithms using these biomarkers to tailor surgical and adjuvant therapy for specific diffuse gliomas.