Nodal Recurrence Appears Low After Neoadjuvant Chemotherapy in Node+ Breast Cancer
March 24th 2022Patients with clinically lymph node–positive breast cancer who achieved cN0 disease following treatment neoadjuvant chemotherapy with 3 or more negative sentinel lymphoma nodes identified by sentinel lymphoma node biopsy alone had a decrease in nodal recurrence.
FDA Approves 177Lu-PSMA-617 for Pretreated PSMA+ Metastatic Castration-Resistant Prostate Cancer
March 23rd 2022Based on data from the phase 3 VISION trial, 177Lu-PSMA-617 may now be used to treat patients who were previously treated with androgen receptor pathway inhibitors plus taxane-based chemotherapy for metastatic prostate specific membrane antigen–positive castration-resistant prostate cancer.
Updated Analysis of Nivolumab Plus Ipilimumab Combos Highlights Long OS for Advanced Melanoma
March 23rd 2022The 6.5-year updated analysis of the phase 3 CheckMate 067 trial highlighted notable overall survival benefit with nivolumab alone or in combination with ipilimumab for patients with advanced melanoma.
Merseburger Discusses Future Research of PRESIDE Trial Enzalutamide Combo
March 23rd 2022Axel Merseburger, MD, PhD, spoke about implementing the treatment combination of enzalutamide plus docetaxel/prednisone for progressive castration-resistant prostate cancer from the PRESIDE trial into the real-world.
Proposed Legislation Could Put Expiration Date on Accelerated Approvals
March 22nd 2022Maurie Markman, MD, sits down with CancerNetwork® to discuss proposed legislation that would put a time limit on how long drugs with an accelerated approval can stay on the market, and how that may negatively impact patients with cancer.
Fast Track Designation Granted to Novel Immunostimulant 7HP349 in Anti–PD-1 Resistant Melanoma
March 21st 20227HP340 was granted fast track designation in combination with an anti–CTLA-4 treatment by the FDA for patients with unresectable or malignant melanoma for whom PD-1 inhibition therapy has failed.
Individualized Starting Dose of Maintenance Niraparib Increases PFS vs Placebo in Ovarian Cancer
March 20th 2022The phase 3 PRIME study showed increased progression-free survival for patients with newly diagnosed ovarian cancer who were treated with an individualized starting dose of maintenance niraparib vs placebo.