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In patients with HER2-positive breast cancer undergoing trastuzumab therapy, elevated troponin I or T before the treatment is associated with an increased risk of trastuzumab-related cardiac dysfunction.

A study presented last month at ASTRO found that a boost of radiation therapy following lumpectomy in DCIS patients resulted in reduced rates of local recurrence.

A new study from the ACS indicates that the proportion of cancer deaths from cigarette smoking varies substantially by state, but is highest in the South where as many as 40% of cancer deaths in men are smoking-related.

A study presented last month at ASTRO found that better radiation outcomes for head and neck cancer were associated with higher facility volume.

Common breast cancer risk alleles are correlated with both the incidence of breast cancer and mortality, and using these alleles along with other factors could identify women at very low risk of breast cancer who could potentially avoid mammography.

Dr. Alan Blum and Cancer Network have partnered to assemble a four-part slideshow series addressing the history of America’s smoking pandemic. Part 4 highlights a period of further regulation on the tobacco industry, the advent of e-cigarettes, and more.

Venous thromboembolism is significantly more likely over the long term in breast cancer patients than in the general population, according to a study in Sweden.

Due to the delicate hemostatic balance in cancer patients, an understanding of both the clotting and bleeding risks in this population is crucial to effectively manage hematologic complications.

In this interview we discuss the CRISPR technology currently being used to “edit” genes and when we might see the technology in mainstream practice.

A study of patients receiving rituximab therapy found that screening for hepatitis B virus infection (HBV) was suboptimal, and some patients who did not receive antiviral treatment experienced HBV reactivation or flare. Screening rates, however, do appear to be improving over time.

Former chairs of the USPSTF are questioning whether it may be time to alter the relationship between the USPSTF and determinations of preventive services coverage under the Patient Protection and Affordable Care Act.

A new study has found that the price of older drugs increased more between 2010 and 2015 than that of newer drugs, with some having undergone dramatic price increases.

Prediagnosis obesity as measured by body mass index was a risk factor for overall and individual secondary primary cancers in a study of male cancer survivors.

Are you up to date on the latest FDA approvals in advanced breast cancer? How about the latest findings presented at this year’s ESMO Congress?

Do you know what factors increase the risk of melanoma? How about the ins and outs of T staging? Test your knowledge on these topics and more in our latest quiz.

Likely, most doctors would say they are good listeners. It is an essential skill when studying and practicing medicine. But under stress of limited time or a patient not responding to treatment-maybe our ability suffers a bit. Perhaps we are listening but also talking and not checking for understanding.

Colonoscopy screening is modestly effective for preventing colorectal cancer in patients aged 70 to 74, but the benefits may begin to diminish after that.

More than 80% of patients referred for consideration in a phase I clinical trial were still willing to participate after a consultation where they learned more about trial participation.

Pneumonitis occurs in approximately 5% of cancer patients treated with anti–PD-1/PD-L1 immunotherapy agents.

Are you up to date on the latest incidence and mortality numbers in melanoma? How about radiotherapy and drug interactions? Test your knowledge in our latest quiz.

The dilemma for clinicians is how best to understand and manage this rapidly growing body of information to improve patient care. With millions of genetic variants of potential clinical significance and thousands of genes associated with rare but well-established genetic conditions, the complexities of genetic data management clearly will require improved computerized clinical decision support tools, as opposed to continued reliance on traditional rote, memory-based medicine.

Panel testing has important advantages but is being misused due to payer constraints and laboratory marketing pressures. Much testing is haphazard and results in utilization of limited genetic counseling resources in the discussion of variants of uncertain significance and low-penetrance gene mutations.

Current guidelines recommend antimicrobial prophylaxis with fluoroquinolones in patients at high risk for infection-related morbidity and mortality, but this practice provides a short-term benefit to individual patients.

In this interview we review recent breast cancer screening guidelines from the ACS and USPSTF, and discuss the changing way that early-stage breast and prostate cancers are being treated.

Patients with advanced cancer treated with the peripheral μ-opioid receptor antagonist methylnaltrexone had longer overall survival.

Survivors of childhood cancers are at significantly increased risk of cardiotoxicity if treated with anthracyclines, according to a new review of the literature.

Cancer screening recommendations for organ transplant recipients are inconsistent across international clinical practice guidelines, according to a new study.

Many patients who receive prescription drugs get them from dispensing physician practices. Since 2006, these dispensaries have participated as in-network providers for various Medicare Part D pharmacy networks; however, now physician dispensaries are in danger of being reclassified as out-of-network.

Are you up to date on the known risk factors for multiple myeloma? How about the latest findings presented at this year’s ASCO meeting?

The International Agency for Research on Cancer Working Group recently released an updated evaluation of evidence connecting body fatness and cancer.