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Opinion|Videos|December 3, 2024

Bispecifics in R/R MM: AE Management and Sequencing

Author(s)Joseph R. Mikhael, MD

Panelist discusses how every drug oncologists use comes with adverse events (AEs), and with bispecifics they are seeing a similar AE profile to that seen in CAR T-cell therapy. There are 3 major AEs: cytokine release syndrome, neurological toxicity, and infections. To manage AEs, oncologists are now monitoring patients more intensely as well as engaging with the patient’s family to provide updates on the status of the patient.

Episodes in this series

2 experts are featured in this video

EP. 1 R/R MM: Treating Patients with CNS Metastases Involvement

2 experts are featured in this video

EP. 2 Optimal Dosing Strategies and Managing AEs

2 experts are featured in this video

EP. 3 R/R MM: Bispecifics in R/R MM: Key Takeaways

1 expert in this video

EP. 4 R/R MM: Insights Into Optimal Dosing for Bispecifics

1 expert in this video

EP. 5 Bispecifics in R/R MM: AE Management and Sequencing

1 expert in this video

EP. 6 Future Perspectives in R/R MM

1 expert in this video

EP. 7 R/R MM Treatment Landscape: Role of Bispecifics

1 expert in this video

EP. 8 Clinical Pearls Surrounding the Use of Bispecifics in R/R MM

Video content above is prompted by the following

What AEs are you seeing in practice with bispecifics?
What are some strategies used to manage them?
What is your current approach to sequencing bispecifics (BCMA vs non-BCMA bispecific, CAR T vs bispecifics)?
What insights can you share for fellow oncologists regarding sequencing?

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