Clinical Pearls Surrounding the Use of Bispecifics in R/R MM

Opinion
Video

Dr Nadeem discusses his case details and shares his initial thoughts. He then reviews the current treatment landscape for relapsed/refractory multiple myeloma, including his experience with bispecifics in practice and his challenges in using them. Dr Nadeem discusses his approach to sequencing bispecifics vs chimeric antigen receptor T-cell therapies, including B-cell maturation antigen (BCMA) and non-BCMA bispecifics, and the factors he considers, followed by key takeaways from a recent meeting on bispecifics in relapsed/refractory multiple myeloma, focusing on dosing, adverse event management, and clinical pearls for oncologists.

Video content above is prompted by the following

  • How do you approach sequencing (bispecifics vs chimeric antigen receptor T-cell or B-cell maturation antigen [BCMA] bispecific vs non-BCMA bispecific) in your practice?
  • What factors do you consider?
  • Please share your key takeaways from that meeting, especially surrounding the use of bispecifics (dosing, adverse event management) in relapsed/refractor multiple myeloma (R/R MM).
  • What clinical pearls can you share with fellow medical oncologists considering the use of bispecifics in R/R MM?
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