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Opinion|Videos|December 23, 2024

Future Perspectives in HER2+ Breast Cancer

Author(s)Neil M. Iyengar, MD, Odessa Williams, NP, ANCC, Dorian Nygard

Panelists discuss emerging regimens and agents being explored for the future treatment of advanced HER2+ breast cancer, highlighting the potential innovations that may improve patient outcomes.

Episodes in this series

EP. 1 Overview of HER2 Breast Cancer

EP. 1 Overview of HER2 Breast Cancer

EP. 2 HER2+ Breast Cancer Diagnosis: Insights From Patients and Clinicians

EP. 2 HER2+ Breast Cancer Diagnosis: Insights From Patients and Clinicians

EP. 3 Coordinating Care for HER+ Breast Cancer Patients: A Multidisciplinary Approach

EP. 3 Coordinating Care for HER+ Breast Cancer Patients: A Multidisciplinary Approach

EP. 4 Multidisciplinary Care of HER2+ Breast Cancer: A Patient Perspective

EP. 4 Multidisciplinary Care of HER2+ Breast Cancer: A Patient Perspective

EP. 5 Tailoring Patient Education and Resources in HER2+ Breast Cancer

EP. 5 Tailoring Patient Education and Resources in HER2+ Breast Cancer

EP. 6 Navigating HER2+ Breast Cancer Treatment: A Patient's Journey

EP. 6 Navigating HER2+ Breast Cancer Treatment: A Patient's Journey

EP. 7 Navigating Systemic Therapy Options in HER2+ Breast Cancer

EP. 7 Navigating Systemic Therapy Options in HER2+ Breast Cancer

EP. 8 Key Insights from the HER2CLIMB Trial

EP. 8 Key Insights from the HER2CLIMB Trial

EP. 9 Key Insights From the DEBBRAH and HER2CLIMB-02 Studies

EP. 9 Key Insights From the DEBBRAH and HER2CLIMB-02 Studies

EP. 10 BRIDGET Trial: Strategies in Maintenance Therapy for HER2+ Breast Cancer with Brain Metastases

EP. 10 BRIDGET Trial: Strategies in Maintenance Therapy for HER2+ Breast Cancer with Brain Metastases

EP. 11 Preparing Patients for Treatment: Education, Administration and Adverse Effect Management in HER2+ Breast Cancer

EP. 11 Preparing Patients for Treatment: Education, Administration and Adverse Effect Management in HER2+ Breast Cancer

EP. 12 Patient Perspectives on Managing Adverse Effects from Capecitabine, Trastuzumab, and Tucatinib

EP. 12 Patient Perspectives on Managing Adverse Effects from Capecitabine, Trastuzumab, and Tucatinib

EP. 13 Comprehensive Supportive Care for Metastatic HER2+ Breast Cancer

EP. 13 Comprehensive Supportive Care for Metastatic HER2+ Breast Cancer

EP. 14 Patient Perspective: Key Aspects of Supportive Care in the HER2+ Breast Cancer Journey

EP. 14 Patient Perspective: Key Aspects of Supportive Care in the HER2+ Breast Cancer Journey

EP. 15 Future Perspectives in HER2+ Breast Cancer

EP. 15 Future Perspectives in HER2+ Breast Cancer

EP. 16 Closing Thoughts: Key Messages for Clinicians and Patients in the Treatment of HER2+ Breast Cancer

EP. 16 Closing Thoughts: Key Messages for Clinicians and Patients in the Treatment of HER2+ Breast Cancer

EP. 17 Discussing, Managing, and Treating HER2+ Breast Cancer From the Patient’s Perspective

EP. 17 Discussing, Managing, and Treating HER2+ Breast Cancer From the Patient’s Perspective

Dr Iyengar: At a high level, what new regimens or agents are being explored that you are hopeful for in the future treatment of advanced HER2+ breast cancer?

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Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

Balazs Halmos, MD, MS; Enriqueta Felip, MD, PhD; Julia Rotow, MD

Breast Cancer Tumor Board: Targeting TROP2 – Innovations in Triple-Negative Breast Cancer Treatment

Breast Cancer Tumor Board: Targeting TROP2 – Innovations in Triple-Negative Breast Cancer Treatment

Joyce O’Shaughnessy, MD; Matthew P. Goetz, MD; Hope S. Rugo, MD, FASCO

Evaluating the Latest Data and Ongoing Trials for Novel ADC Approaches in TNBC

Evaluating the Latest Data and Ongoing Trials for Novel ADC Approaches in TNBC

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD

Establishing the Rationale for ADC and ICI Combinations in TNBC

Establishing the Rationale for ADC and ICI Combinations in TNBC

Virginia Kaklamani, MD, DSc; Tiffany A. Traina, MD, FASCO

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Filipa Lynce, MD; Rita Nanda, MD

Breaking Down the Rationale for Targeting TROP2 in TNBC

Breaking Down the Rationale for Targeting TROP2 in TNBC

Filipa Lynce, MD; Rita Nanda, MD

Optimizing Treatment for Biliary Tract Cancers

Optimizing Treatment for Biliary Tract Cancers

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Broadening the Frontline—Studies Informing the Use of Immunotherapy in Hepatocellular Carcinoma

Broadening the Frontline—Studies Informing the Use of Immunotherapy in Hepatocellular Carcinoma

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Cross-Disease Integration of Immunotherapy Innovations

Cross-Disease Integration of Immunotherapy Innovations

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Expert Roundtable and Panel Discussions: Current and Future Landscape of TNBC

Expert Roundtable and Panel Discussions: Current and Future Landscape of TNBC

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Tiffany A. Traina, MD, FASCO

Show Me the Data®: New and Emerging Roles for Oral SERD Therapy in the Treatment of ER+/HER2– Breast Cancer

Show Me the Data®: New and Emerging Roles for Oral SERD Therapy in the Treatment of ER+/HER2– Breast Cancer

Ana C. Garrido-Castro, MD; Pedram Razavi, MD, PhD

Practical Considerations and Future Directions for New Treatment Strategies in SCLC

Practical Considerations and Future Directions for New Treatment Strategies in SCLC

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Misty D. Shields, MD, PhD

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc; Filipa Lynce, MD; Rita Nanda, MD; Tiffany A. Traina, MD, FASCO

Radioligand Therapy 101: The Science Behind the Strategy

Radioligand Therapy 101: The Science Behind the Strategy

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

Working Together: Overcoming Barriers to Optimize Outcomes in Patients Treated With Radioligand Therapy Through Multidisciplinary Care

Working Together: Overcoming Barriers to Optimize Outcomes in Patients Treated With Radioligand Therapy Through Multidisciplinary Care

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Nerina McDonald, MSPAS, PA-C; Scott T. Tagawa, MD, MS, FACP, FASCO

21st Annual New York Lung Cancers Symposium®

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21st Annual New York Lung Cancers Symposium®

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Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Geoffery Ku, MD; Shruti Patel, MD

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Jason Hafron, MD; Aaron D. Berger, MD; Arpeet Shah, MD

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Yana G. Najjar, MD; Sapna Patel, MD

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