Key Insights from the HER2CLIMB Trial

Opinion
Video

Panelists discuss key data from the HER2CLIMB study, which evaluates the efficacy of tucatinib (Tukysa) in combination with trastuzumab (Herceptin) and capecitabine (Xeloda) for patients with advanced HER2+ breast cancer, highlighting outcomes across patient subgroups and the clinical significance of findings related to patients with measurable baseline intracranial disease.

  1. Dr Iyengar: Briefly discuss key data from the HER2CLIMB study, evaluating tucatinib in combination with trastuzumab and capcitabine capecitabine for patients with advanced HER2+ breast cancer.
    1. Please comment on the efficacy outcomes across patient subgroups.
    2. What is the clinical significance for findings in patients with advanced HER2+ breast cancer and measurable baseline intracranial disease?

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