September 3rd 2024
“I don't think [the CRL] impacts how I look at the data that is publicly available and the approval chances long term for linvoseltamab and how we might use it in the future,” said Surbhi Sidana, MD.
Applying New Evidence in Multiple Myeloma Care from Frontline to R/R Disease
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Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board
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Annual Hematology Meeting: Preceding the 66th ASH Annual Meeting and Exposition
December 6, 2024
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Community Oncology Connections™: Overcoming Barriers to Testing, Trial Access, and Equitable Care in Cancer
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Translating New Evidence into Treatment Algorithms from Frontline to R/R Multiple Myeloma: How the Experts Think & Treat
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Medical Crossfire: How Has Iron Supplementation Altered Treatment Planning for Patients with Cancer-Related Anemia?
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Medical Crossfire®: The Experts Bridge Recent Data in Chronic Lymphocytic Leukemia With Real-World Sequencing Questions
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Community Practice Connections™: Pre-Conference Workshop on Immune Cell-Based Therapy
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Fighting Disparities and Saving Lives: An Exploration of Challenges and Solutions in Cancer Care
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CD34+ Cell Selection Reduces Tumor Cell Contamination in Myeloma Stem Cell Transplants
February 1st 1999TORONTO-CD34+ selection of peripheral blood stem cells (PBSCs) significantly reduces tumor cell contamination while providing safe and rapid hematologic recovery for multiple myeloma patients receiving myeloablative therapy, Dr. A.K. Stewart, of Toronto Hospital, reported at ASH.
Older Multiple Myeloma Patients Can Be Offered High-Dose Chemo/Transplant’
February 1st 1999LONDON-Although age is currently used as an eligibility criteria for inclusion in transplant protocols, a retrospective study from the Royal Marsden Hospital, London, suggests that multiple myeloma patients in their 60s and 70s can safely undergo high-dose chemotherapy with autologous bone marrow or stem cell transplantation.
New Publications About Bone Marrow Transplant Available for Patients
May 1st 1998Bone marrow transplantation (BMT) is now recognized as standard treatment for many diseases. Patients with cancer, especially those with certain types of leukemia, lymphoma, breast and ovarian cancers, multiple myeloma, and aplastic
Keys to Success of BMT Programs in Managed Care Era
May 1st 1998Although creating and sustaining a successful bone marrow transplant (BMT) program poses tricky challenges in today’s rapidly evolving managed care environment, it can be done, says Albert B. Einstein, Jr., MD, associate director for clinical
Clinical Trial of New Agent to Overcome MDR Resistance in Multiple Myeloma Patients
December 1st 1997Marshfield Cancer Center, the lead investigation site for a National Cancer Institute-sponsored multicenter clinical trial, announced it is seeking patients to participate in a study of a potential new treatment, PSC 833, to overcome chemotherapy resistance in relapsing or refractory multiple myeloma. The study, coordinated by the Eastern Cooperative Oncology Group (ECOG), is seeking to enroll 360 patients throughout the United States and Canada.
Multiple Myeloma Patients Needed for Trial of MDR Reverser
October 1st 1997BOSTON-The Eastern Cooperative Oncology Group (ECOG) is seeking to enroll 360 multiple myeloma patients with relapsing or refractory disease for a study of PSC 833, a cyclosporin D analog that may be able to reverse chemotherapy resistance. The trial will randomize patients to receive PSC 833 plus standard VAD (vincristine, Adriamycin, and dexamethasone) or standard VAD alone.
Bisphosphonates Improve QOL in Bone Lesion Patients
September 1st 1997BETHESDA, Md-Less than two years ago, the FDA approved Aredia (pamidronate disodium for injection) as the first agent for the treatment of osteo-lytic bone lesions in multiple myeloma patients, to be used in conjunction with standard antimyeloma chemotherapy.
Comments on Bone Marrow Transplantation for Multiple Myeloma
June 1st 1996Multiple myeloma is a malignant disease characterized by excess proliferation of monoclonal plasma cells. Its progression leads to bone marrow failure, increased risk of infection, and painful osteolytic bony lesions. Although patients are most often
HDC/ABMT Has Benefits in Multiple Myeloma
January 1st 1996SEATTLE--French researchers have recently concluded a study of multiple myeloma in which high-dose chemotherapy combined with autologous bone marrow transplantation (HDC/ABMT) resulted in a significant improvement in response rate and overall survival, compared with conventional chemotherapy.
Arkansas Pioneers 'Total Therapy' for Multiple Myeloma
January 1st 1996LITTLE ROCK, Ark--Little prog-ress has been made during the last 30 years toward improving the prognosis of patients with myeloma. Because of the patients' often brittle condition and advanced age, dose intensity concepts had not been evaluated until the late Tim McElwain from the Royal Marsden Hospital reported responses to high-dose melphalan [Alkeran] at 140 mg/m² in patients with refractory disease or high-risk newly diagnosed patients.
Pamidronate Relieves Pain, Reduces Analgesic Use in Multiple Myeloma
November 1st 1995LUXEMBOURG-The bisphos-phonate pamidronate (Aredia) not only reduced skeletal morbidity but also relieved pain, reduced analgesic use, and improved quality of life in a multicenter study reported at the 7th International Symposium of the Multinational Association of Supportive Care in Cancer.
Aredia Recommended for New Indication in Multiple Myeloma
September 1st 1995ROCKVILLE, Md--In a move with very little precedent, the FDA Oncologic Drugs Advisory Committee (ODAC) recommended approval of a new indication for the bisphosphonate Aredia (pam-idronate disodium for injection) on the basis of a single clinical trial.