Radiation concerns merge for airports and radiation oncology
August 25th 2010Earlier this month two senators introduced the “Consistency, Accuracy, Responsibility, and Excellence in Medical Imaging and Radiation Therapy Act of 2010.” Sens. Mike Enzi (R-Wyo.) and Tom Harkin (D-Iowa) hope through this legislation to guarantee that staff who perform medical imaging and radiation therapy are appropriately qualified by establishing standards for these personnel. It makes sense. Who wants unqualified personnel performing procedures involving ionizing radiation?
Call for authors: Oncology’s new Practice & Policy section accepting submissions
August 17th 2010The passage of MMA changed the oncology practice landscape, now we’re entering into unknown territory with Obama’s reform bill. Voice your opinions/perspectives on practice and policy issues affecting cancer care with 35,000 of your colleagues on the pages of ONCOLOGY.
New Knowledge About Cancer in HIV's Survivors Prompts Warnings of an Epidemic
August 17th 2010We cannot escape the realities of biology. Just as children rescued from leukemia and lymphoma live to grow into adults who must confront the adverse effects of their curative treatment, people rescued from AIDS by HAART (highly active antiretroviral therapy) are showing a substantially increased risk of cancers other than the "AIDS-defining" malignancies designated by the Centers for Disease Control in the 1980s: Kaposi sarcoma, non-Hodgkin lymphoma (NHL), and cervical cancer.
Intensity-Modulated Radiation Therapy for Anal Cancer: Toxicity versus Outcomes
August 15th 2010The treatment of cancer of the anal canal has changed significantly over the past several decades. Although the abdominoperineal resection (APR) was the historical standard of care, a therapeutic paradigm shift occurred with the seminal work of Nigro, who reported that anal canal cancer could be treated with definitive chemoradiation, with APR reserved for salvage therapy only. This remains an attractive approach for patients and physicians alike and the standard of care in this disease. Now, nearly four decades later, a similar approach continues to be utilized, albeit with higher radiation doses; however, this strategy remains fraught with considerable treatment-related morbidities. With the advent of intensity-modulated radiation therapy (IMRT), many oncologists are beginning to utilize this technology in the treatment of anal cancer in order to decrease these toxicities while maintaining similar treatment efficacy. This article reviews the relevant literature leading up to the modern treatment of anal canal cancer, and discusses IMRT-related toxicity and disease-related outcomes in the context of outcomes of conventionally treated anal cancer.