Amgen to Acquire Abgenix
THOUSAND OAKS, California—Amgen and Abgenix, Inc. (Fremont, California) have signed a definitive merger agreement under which Amgen will acquire Abgenix for approximately $2.2 billion in cash plus the assumption of debt. The acquisition of Abgenix provides Amgen with full ownership of one of its most important advanced pipeline products, panitumumab. The agent, which inhibits the epidermal growth factor receptor (EGFR), has shown significant improvement in progression-free survival for metastatic colorectal cancer patients who have failed standard chemotherapy (see ONI December 2005, page 14). Abgenix also brings to the merger its proprietary fully human monoclonal antibody technology, XenoMouse.
THOUSAND OAKS, CaliforniaAmgen and Abgenix, Inc. (Fremont, California) have signed a definitive merger agreement under which Amgen will acquire Abgenix for approximately $2.2 billion in cash plus the assumption of debt. The acquisition of Abgenix provides Amgen with full ownership of one of its most important advanced pipeline products, panitumumab. The agent, which inhibits the epidermal growth factor receptor (EGFR), has shown significant improvement in progression-free survival for metastatic colorectal cancer patients who have failed standard chemotherapy (see ONI December 2005, page 14). Abgenix also brings to the merger its proprietary fully human monoclonal antibody technology, XenoMouse.
FDA Approves Encorafenib/Cetuximab Plus mFOLFOX6 for Advanced BRAF V600E+ CRC
December 20th 2024The FDA has granted accelerated approval to encorafenib in combination with cetuximab and mFOLFOX6 for patients with metastatic colorectal cancer with a BRAF V600E mutation, as detected by an FDA-approved test.
