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Opinion|Videos|December 14, 2023

KRYSTAL-7: Efficacy and Safety of Adagrasib with Pembrolizumab in Patients With Advanced KRASG12C Mutated NSCLC

Author(s)Narjust Florez, MD

KRYSTAL-7 is a study exploring the efficacy of adding adagrasib to first-line pembrolizumab in patient with NSCLC with varying PD-L1 expression levels, showing promising response rates and progression-free survival, but also adverse events like hepatotoxicity.

Episodes in this series

EP. 1 Current Treatment Landscape for KRASG12C-Mutated NSCLC

EP. 1 Current Treatment Landscape for KRASG12C-Mutated NSCLC

EP. 2 Treatment Options for KRASG12C Mutated NSCLC

EP. 2 Treatment Options for KRASG12C Mutated NSCLC

EP. 3 KRYSTAL-1: Follow-Up Data on Adagrasib Monotherapy in Patients with Advanced/Metastatic KRASG12C Mutated NSCLC

EP. 3 KRYSTAL-1: Follow-Up Data on Adagrasib Monotherapy in Patients with Advanced/Metastatic KRASG12C Mutated NSCLC

EP. 4 KRYSTAL-7: Efficacy and Safety of Adagrasib with Pembrolizumab in Patients With Advanced KRASG12C Mutated NSCLC

EP. 4 KRYSTAL-7: Efficacy and Safety of Adagrasib with Pembrolizumab in Patients With Advanced KRASG12C Mutated NSCLC

EP. 5 Long-Term Outcomes of Sotorasib Efficacy in Patients With KRASG12C Mutated NSCLC

EP. 5 Long-Term Outcomes of Sotorasib Efficacy in Patients With KRASG12C Mutated NSCLC

EP. 6 Hepatotoxicity with KRASG12C Inhibitors in NSCLC

EP. 6 Hepatotoxicity with KRASG12C Inhibitors in NSCLC

EP. 7 Sotorasib Versus Docetaxel for Previously Treated Patients With KRASG12C Mutated NSCLC: Data From CodeBreaK 200

EP. 7 Sotorasib Versus Docetaxel for Previously Treated Patients With KRASG12C Mutated NSCLC: Data From CodeBreaK 200

EP. 8 Managing CNS Metastases in KRASG12C Mutated NSCLC

EP. 8 Managing CNS Metastases in KRASG12C Mutated NSCLC

EP. 9 Future Directions in KRASG12C Mutated NSCLC

EP. 9 Future Directions in KRASG12C Mutated NSCLC

EP. 10 Experts Examine the Need for Targeted Therapy Options for KRAS G12C–Mutated NSCLC

EP. 10 Experts Examine the Need for Targeted Therapy Options for KRAS G12C–Mutated NSCLC

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