Olverembatinib Study in Patients With Heavily Pretreated Chronic Myeloid Leukemia
A comprehensive review of chronic myeloid leukemia olverembatinib data led by expert Kebede Begna, MD, from the Mayo Clinic team.
Relapsed/Refractory Multiple Myeloma: The ALLIANCE A061202 Study
Adeel Khan, MD, MPH, MS, expert in multiple myeloma management, reviews data from the ALLIANCE A061202 trial of isatuximab + pomalidomide + dexamethasone in relapsed/refractory disease.
Effect of MRD on Adjuvant Therapy and Monitoring Strategies in CRC
Specialists on colorectal cancer discuss the effect of MRD on monitoring strategies and adjuvant therapy decisions for patients with colorectal cancer.
Treatment Considerations for Bispecific Antibodies and Unmet Needs in MM
The expert panel overviews factors to consider with bispecific antibodies and offers closing insights on unmet needs in the multiple myeloma treatment space.
Cross Q&A: Ciltacabtagene Autoleucel in Relapsed/Refractory Multiple Myeloma
Experts from the Mayo Clinic and UT Southwestern share insight on the CARTITUDE-4 study and ciltacabtagene autoleucel in the second cross Q&A session.
Nirogacestat May Offer an Additional Treatment Option for Desmoid Tumors
Brian Van Tine, MD, PhD, also discusses how the treatment of desmoid tumors has evolved following data supporting the use of sorafenib in this population.
Cross Q&A: Arterial Occlusive Events With Ponatinib in the PACE Trial
Following a review of the retrospective analysis of PACE, experts reflect on its importance in understanding the risk of arterial occlusive events with ponatinib.
CRC: Clinical Trial Landscape for MRD-Based Early Intervention
An overview colorectal cancer clinical trials studying early intervention based on MRD positivity.
Relapsed/Refractory Multiple Myeloma: Practice Pearls and Future Directions in Care
Thomas Martin, MD; Ajay Nooka, MD; and Jeremy Larsen, MD, share closing thoughts on the evolving landscape of cytokine release syndrome management in relapsed/refractory multiple myeloma.
‘Unprecedented’ Results Support Dostarlimab Approval in Endometrial Cancer
Dostarlimab plus chemotherapy produces notable benefits among patients with advanced, mismatch repair deficient endometrial cancer in the phase 3 RUBY trial.
Novel Therapies May Lead to More Treatment Options in Sarcoma Subtypes
CAR T-cell therapies and immunotherapy agents may offer up new options and even become standard of care in certain sarcoma subtypes.
Relapsed/Refractory Multiple Myeloma: An Evolving Treatment Landscape
Closing out their program on relapsed/refractory multiple myeloma, Ajai Chari, MD, and Carolina Schinke, MD, consider optimal treatment strategies in the current landscape and look toward future directions in care.
Indirect Comparison of Acalabrutinib Versus Zanubrutinib in RR CLL: Efficacy Analysis
Alan Skarbnik, MD, and Ryan Jacobs, MD, review efficacy data from the indirect comparison study of acalabrutinib versus zanubrutinib in relapsed/refractory chronic lymphocytic leukemia.
The AML Treatment Horizon
Experts on acute myeloid leukemia offer closing thoughts and discuss emerging treatments in the field.
Determining Which Patients Will Benefit the Most From Menin Inhibitor Treatment
The expert panel provide clinical insights on which patients with AML may benefit the most from treatment with menin inhibitors.
The Role of Menin Inhibitors in the AML Treatment Armamentarium
The panel of experts share their thoughts on where menin inhibitors will offer the most benefit in the overall treatment regimen for patients with AML.
Clinical Trials With BTK Inhibitors in Relapsed/Refractory CLL
Focused discussion on key clinical trial data behind currently available BTK inhibitors for patients with relapsed/refractory chronic lymphocytic leukemia.
Emerging Advancements in the Treatment of Clear Cell RCC
The panel highlights novel agents under investigation for the treatment of clear cell renal cell carcinoma.
Expert Reviews Novel Treatment Options Across Sarcoma Subtypes
There are several novel treatments that may be beneficial in several sarcoma subtypes including CAR T-cell therapies and immune checkpoint inhibitors, according to Sandra P. D’Angelo, MD.
Atezolizumab Plus Cabozantinib Versus Cabozantinib Monotherapy for Metastatic RCC
Moshe Ornstein, MD, reviews the design and efficacy and safety data from the phase 3 CONTACT-03 study in metastatic renal cell carcinoma.