High-Dose IL-2 Associated With Improved Response in Renal Cell Carcinoma Patients
September 1st 2001Preliminary results of a phase III trial of high-dose recombinant human interleukin-2 (IL-2, Proleu kin) demonstrated increased response rates with a longer median duration, compared to outpatient subcutaneous IL-2 in conjunction with
Considerations in the Diagnosis and Management of Brain Metastases
September 1st 2001Brain metastases are a common complication of systemic cancer and a significant cause of morbidity. For patients whose brain metastases remain untreated, the prognosis is poor. The advent of contrast-enhanced magnetic
Current Clinical Trials of Epothilone B Analog (BMS-247550)
September 1st 2001BMS-247550 is a methyl, semi-synthetic analog of the natural product epothilone B. Provided to the National Cancer Institute (NCI) by Bristol-Myers Squibb, BMS-247550 was chosen for clinical development because it demonstrated
Considerations in the Diagnosis and Management of Brain Metastases
September 1st 2001Brain metastases are a common complication of systemic cancer and a significant cause of morbidity. For patients whose brain metastases remain untreated, the prognosis is poor. The advent of contrast-enhanced magnetic
Investigator-Initiated Health-Related Quality-of-Life Research
In part I of this series, we identified currently active clinical trials that include health-related quality-of-life (HRQOL) outcomes as a primary or secondary objective of the overall study (Trimble EL et al: ONCOLOGY 15:601-611, 2001). The goal of this
Considerations in the Diagnosis and Management of Brain Metastases
September 1st 2001Brain metastases are a common complication of systemic cancer and a significant cause of morbidity. For patients whose brain metastases remain untreated, the prognosis is poor. The advent of contrast-enhanced magnetic
Clinical Manual for the Oncology Advanced Practice Nurse
September 1st 2001This book is intended to serve as a quick reference for advanced practice nurses (APNs) caring for oncology patients, from diagnosis through treatment and rehabilitation. With the advances made over the past several years in prevention, early