Cover Story High cost of biologics takes a toll on hem/onc practices FDA cracks down on counterfeit cancer cure products DEPARTMENTS Focus on Breast Cancer Mastectomy rates for early breast cancer are on the upswing at one Mayo Clinic Is breast MRI primed for widespread use as a high-risk screening tool? Vantage Point: Risk factors will guide the imaging paradigm Focus on Lung Cancer Anti-IGF-1R antibody plus chemo active in advanced non-small-cell lung cancer News & Analysis Oncologic drug safety: Separating fact from fiction Focus on Prostate Cancer Dual antiangiogenic therapy plus chemo is active in advanced prostate cancer