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Opinion|Videos|January 10, 2025

Dosing Strategies in Different Targets Bispecifics

Author(s)Douglas Sborov, MD, MS, Mary Steinbach, NP, Kelley Julian, PharmD, BCOP

Panelists note that while both teclistamab and elranatamab are weekly doses, elranatamab is a flat dose, and physicians have seen quick and positive responses to elranatamab treatment and physicians have seen…treatment and have been able to pull back patients from doses earlier to prevent an increase in adverse effects from infection.

Episodes in this series

3 experts in this video

EP. 1 Meet a 76-Year-Old Patient With Late-Line R/R MM, Unsuitable For CAR T Therapy

3 experts in this video

EP. 2 Role of Step-Up Dosing

3 experts in this video

EP. 3 Dosing Frequency, and Adverse Event Management With Bispecific Therapy

3 experts in this video

EP. 4 Strategies For Management of Infections

3 experts in this video

EP. 5 Optimizing Treatment Goals and Supportive Care For Relapsed/Refractory Multiple Myeloma in Older Patients

3 experts in this video

EP. 6 Meet a 55-Year-Old Who Was Refractory to or Relapsed on BCMA CAR T Therapy

3 experts in this video

EP. 7 Patient Tolerability of Talquetamab and Use of IVIG

3 experts in this video

EP. 8 Strategizing Talquetamab Use In Relapsed/Refractory Multiple Myeloma: Balancing Efficacy, Infection Control, and Next-Line Therapy

3 experts in this video

EP. 9 Meet our 61-Year-Old Patient With Late-Line R/R on a BCMA-Targeting Bispecific

3 experts in this video

EP. 10 Dosing Strategies in Different Targets Bispecifics

3 experts in this video

EP. 11 Managing CNS and Systemic Responses In R/R MM: Monitoring and Sequencing Strategies with Elranatamab and Cilta-Cel

EP. 12 Handling an Intricate Case of R/R MM With BCMA/GPRC5D Bispecific Antibodies

EP. 12 Handling an Intricate Case of R/R MM With BCMA/GPRC5D Bispecific Antibodies

Video content above is prompted by the following:

Highlight some of the key dosing differences between teclistamab and elranatamab? Is there anything different regarding elranatamab regarding supportive care?

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