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Opinion|Videos|January 3, 2025

Patient Tolerability of Talquetamab and Use of IVIG

Author(s)Douglas Sborov, MD, MS, Mary Steinbach, NP, Kelley Julian, PharmD, BCOP

Panelists discuss how recent PET is reviewed with the patient, and there is evidence of near resolution of PET avid EMD lesions, though they will continue to monitor adenopathy – most suspicious for a reactive process. For patients treated with IVIG, the goal is to maintain a biological level of IgG at 400 mg/dL.

Episodes in this series

3 experts in this video

EP. 1 Meet a 76-Year-Old Patient With Late-Line R/R MM, Unsuitable For CAR T Therapy

3 experts in this video

EP. 2 Role of Step-Up Dosing

3 experts in this video

EP. 3 Dosing Frequency, and Adverse Event Management With Bispecific Therapy

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EP. 4 Strategies For Management of Infections

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EP. 5 Optimizing Treatment Goals and Supportive Care For Relapsed/Refractory Multiple Myeloma in Older Patients

3 experts in this video

EP. 6 Meet a 55-Year-Old Who Was Refractory to or Relapsed on BCMA CAR T Therapy

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EP. 7 Patient Tolerability of Talquetamab and Use of IVIG

3 experts in this video

EP. 8 Strategizing Talquetamab Use In Relapsed/Refractory Multiple Myeloma: Balancing Efficacy, Infection Control, and Next-Line Therapy

3 experts in this video

EP. 9 Meet our 61-Year-Old Patient With Late-Line R/R on a BCMA-Targeting Bispecific

3 experts in this video

EP. 10 Dosing Strategies in Different Targets Bispecifics

3 experts in this video

EP. 11 Managing CNS and Systemic Responses In R/R MM: Monitoring and Sequencing Strategies with Elranatamab and Cilta-Cel

EP. 12 Handling an Intricate Case of R/R MM With BCMA/GPRC5D Bispecific Antibodies

EP. 12 Handling an Intricate Case of R/R MM With BCMA/GPRC5D Bispecific Antibodies

Video content above is prompted by the following:

Please walk through the patient’s treatment course on talquetamab, including what issues you have seen and how they have been dealt with.
How do physicians think differently about the use of IVIGs for patients treated with talquetamab?

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