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Opinion|Videos|January 3, 2025

Strategizing Talquetamab Use In Relapsed/Refractory Multiple Myeloma: Balancing Efficacy, Infection Control, and Next-Line Therapy

Author(s)Douglas Sborov, MD, MS, Mary Steinbach, NP, Kelley Julian, PharmD, BCOP

Panelists discuss how a patient who is neutropenic is given supportive care with GCSF, as do patients who have prolonged neutropenia, then that patient will be on antibiotic and antifungal prophylaxis.

Episodes in this series

3 experts in this video

EP. 1 Meet a 76-Year-Old Patient With Late-Line R/R MM, Unsuitable For CAR T Therapy

3 experts in this video

EP. 2 Role of Step-Up Dosing

3 experts in this video

EP. 3 Dosing Frequency, and Adverse Event Management With Bispecific Therapy

3 experts in this video

EP. 4 Strategies For Management of Infections

3 experts in this video

EP. 5 Optimizing Treatment Goals and Supportive Care For Relapsed/Refractory Multiple Myeloma in Older Patients

3 experts in this video

EP. 6 Meet a 55-Year-Old Who Was Refractory to or Relapsed on BCMA CAR T Therapy

3 experts in this video

EP. 7 Patient Tolerability of Talquetamab and Use of IVIG

3 experts in this video

EP. 8 Strategizing Talquetamab Use In Relapsed/Refractory Multiple Myeloma: Balancing Efficacy, Infection Control, and Next-Line Therapy

3 experts in this video

EP. 9 Meet our 61-Year-Old Patient With Late-Line R/R on a BCMA-Targeting Bispecific

3 experts in this video

EP. 10 Dosing Strategies in Different Targets Bispecifics

3 experts in this video

EP. 11 Managing CNS and Systemic Responses In R/R MM: Monitoring and Sequencing Strategies with Elranatamab and Cilta-Cel

EP. 12 Handling an Intricate Case of R/R MM With BCMA/GPRC5D Bispecific Antibodies

EP. 12 Handling an Intricate Case of R/R MM With BCMA/GPRC5D Bispecific Antibodies

Video content above is prompted by the following:

Given the patient’s history of frequent infections, how would you balance talquetamab’s efficacy with the need for infection control, and what supportive measures might you prioritize?
How would you approach treatment sequencing if the patient progresses on talquetamab, and what criteria would you use to determine the next line of therapy?

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