
- Oncology NEWS International Vol 4 No 4
- Volume 4
- Issue 4
Receptagen to Develop 'Growth Blocker' Monoclonal Antibody
SEATTLE--Receptagen Ltd. has begun formal clinical development of its first "growth blocker" drug, based on promising laboratory studies. The agent, a monoclonal antibody that blocks the B12 carrier protein trans-cobalamin II, triggered apoptosis in cancer cells by depleting vitamin B12, an essential enzyme co-factor for cell proliferation, said Receptagen president A. Charles Morgan Jr., PhD.
SEATTLE--Receptagen Ltd. has begun formal clinical developmentof its first "growth blocker" drug, based on promisinglaboratory studies. The agent, a monoclonal antibody that blocksthe B12 carrier protein trans-cobalamin II, triggered apoptosisin cancer cells by depleting vitamin B12, an essential enzymeco-factor for cell proliferation, said Receptagen president A.Charles Morgan Jr., PhD.
Articles in this issue
over 30 years ago
First Results of Avicidin Trialsover 30 years ago
Chemo Patients Often Develop Menstrual Irregularitiesover 30 years ago
Growth Factor Receptor Blockade Moving From Laboratory to Clinicover 30 years ago
Controlled-Release AZT Gets FDA Go-Ahead for New Drug Investigationover 30 years ago
Vinorelbine Plus Chemo Promising in Advanced Diseaseover 30 years ago
Bone Substudy a Part of Tamoxifen Prevention Trialover 30 years ago
Ultrasound Breast Screens Useful in Selected Womenover 30 years ago
New Roles Forecast for Endocrine Therapyover 30 years ago
Antisense Drug Against BCL-2 Effective in Animal Cancer Modelsover 30 years ago
Anticancer Drugs From Zeneca in Regulatory Phase of DevelopmentNewsletter
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