FDA Approval Alert: The Need-to-Know | Sotorasib/Panitumumab in KRAS G12C-Mutated Colorectal Cancer

In January 2025, the FDA approved sotorasib plus panitumumab for patients with KRAS G12C-mutated metastatic colorectal cancer, determined by an FDA-approved test, and for those who have previously received therapy including fluoropyrimidine, oxaliplatin, or irinotecan.

Combining sotorasib with panitumumab may reduce the burden of disease in patients with KRAS G12C-mutated metastatic colorectal cancer.
Sotorasib Combo Has Positive PFS Impact in KRAS G12C-Mutated CRC
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Feb 13, 2025 7:00 PM
Combining sotorasib with panitumumab may reduce the burden of disease in patients with KRAS G12C-mutated metastatic colorectal cancer.
Findings from the CodeBreak 300 study have cemented sotorasib/panitumumab as a third-line treatment option for KRAS G12C-mutated colorectal cancer.
Data Open The Door for Earlier Sotorasib/Panitumumab Use in KRAS G12C+ CRC
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Feb 12, 2025 1:00 PM
Findings from the CodeBreak 300 study have cemented sotorasib/panitumumab as a third-line treatment option for KRAS G12C-mutated colorectal cancer.
Adding panitumumab to sotorasib has yielded higher responses rates in KRAS G12C-mutated CRC compared with prior standards of care.
Sotorasib Combo Approval May Improve PFS, Other Outcomes in KRAS G12C+ CRC
Article
Feb 11, 2025 3:00 PM
Adding panitumumab to sotorasib has yielded higher responses rates in KRAS G12C-mutated CRC compared with prior standards of care.
Sotorasib plus panitumumab may offer improved survival compared with previously approved treatment options in KRAS G12C-mutated colorectal cancer.
Sotorasib Combo Approval is ‘Welcome Step’ in KRAS G12C+ CRC Care
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Feb 10, 2025 9:00 PM
Sotorasib plus panitumumab may offer improved survival compared with previously approved treatment options in KRAS G12C-mutated colorectal cancer.
Results from the CodeBreaK 300 trial helped lead to the approval of sotorasib/panitumumab in KRAS G12C-mutated CRC.
FDA Approves Sotorasib/Panitumumab in KRAS G12C-Mutated CRC
Article
Jan 16, 2025 11:13 PM
Results from the CodeBreaK 300 trial helped lead to the approval of sotorasib/panitumumab in KRAS G12C-mutated CRC.