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BETHESDA, Md--The National Cancer Institute has published a new brochure and opened a new website, both designed to encourage cancer patients to enroll in clinical trials. "Taking Part in Clinical Trials: What Cancer Patients Need to Know" provides an overview of cancer treatment trials and answers questions that patients might have about them. Novartis Pharmaceuticals provided partial funding for the pamphlet.

BETHESDA, Md--In theory, highly active antiretroviral therapies, or HAART, should reduce the incidence of AIDS-related Kaposi’s sarcoma (KS) and non-Hodgkin’s lymphomas (NHL) by improving the immune functioning of HIV-infected individuals. Theory appears to be working out, at least with regard to lowering the risk of KS, according to several papers presented at the NCI’s 2nd National AIDS Malignancy Conference.

Medicare will reimburse cancer patients for granisetron hydrochloride (Kytril) tablets, announced SmithKline Beecham. Granistetron is indicated for the prevention of chemo- therapy-induced nausea and vomiting.

Chemotherapy can improve the quality of life of people with incurable cancer if it is administered with the understanding that, although the disease will not be eradicated, the patient can be made to feel better, said an oncologist at Stanford University Medical Center.

WASHINGTON--The House of Representatives Commerce Committee has posted 39,000 tobacco company documents on its website to allow the public to review the papers and determine for itself whether the tobacco companies are guilty of fraud for hiding knowledge of the health ramifications of smoking.

WASHINGTON--Four scientists, three from the United States and one from Australia, have been named winners of the 1998 General Motors Cancer Research Foundation prizes for individual achievement in cancer research.

FORT LAUDERDALE, Fla--Recently, the FDA approved recombinant interleukin-11 (rIL-11 or oprelvekin, Neumega) for the prevention of severe thrombocytopenia in cancer patients with solid tumors or lymphoma. The availability of platelet growth factors represents a significant breakthrough in oncology, and methods are needed to help incorporate these agents into clinical practice guidelines.

CHICAGO--Magic & Vanity, a Chicago-based boutique especially for female cancer survivors and patients, has launched a catalog featuring many of the unique items in its store.

BETHESDA, Md--Good informed consent improves both recruiting and compliance in clinical trials involving genetic testing, said Robert T. Croyle, PhD, associate professor of psychology, University of Utah.

WASHINGTON--Selma Schimmel, a 15-year cancer survivor, brought a message to an international audience that most of them probably never expected to hear from a radio talk-show host. She urged oncology pharmacists to launch an aggressive outreach program to let cancer patients know that pharmacists can and do answer patients’ questions about chemotherapy and its side effects.

A new study by researchers at St. Jude Children’s Research Hospital, published in the May 1st issue of Cell, has identified an enzyme crucial to the production of red blood cells and platelets.

NEW ORLEANS--Colon cancer-prone mice bred to lack the cyclooxy-genase 1 (COX1) enzyme have the same reduction in tumors as those bred to lack the cyclooxygenase 2 (COX2) enzyme. This result suggests that both forms of COX may encourage tumor development, according to research reported by Patricia Chulada, PhD, at the 89th annual meeting of the American Association for Cancer Research (AACR).

NEW ORLEANS--In a rousing session that opened the American Association for Cancer Research (AACR) 89th annual meeting, scientists reviewed recent good news in the war on cancer, while activists exhorted the audience--laypeople and scientists alike--not to be complacent because more progress is needed.

NEW ORLEANS--An altered adenovirus successfully delivered a normal p53 tumor-suppressor gene to several kinds of tumors, Jo Ann Horowitz, MD, clinical project director for Oncology Clinical Research, Schering-Plough Research Institute, Kenilworth, NJ, reported at the annual meeting of the American Association for Cancer Research.

The need for an article such as the one by Little et al is a clear sign that progress is occurring in the treatment of AIDS-related Kaposi’s sarcoma (KS). Without such progress, there would be no urgent need to refine the tools currently used to evaluate the activity of KS treatment.

Kaposi’s sarcoma (KS) is a frequent cause of morbidity and mortality in patients with human immunodeficiency virus (HIV) infection. Several characteristics of KS pose challenges for the conduct of clinical trials. Kaposi’s

Methods for detecting breast cancer are evolving as new technology provides a wider range of options for screening and definitive diagnosis. In addition to mammography and physical examination, screening techniques now include ultrasonography, technetium-99m sestamibi nuclear scanning, and magnetic resonance imaging.

A decade has passed since the first stereotactic-guided histologic breast biopsy was performed. Initially, the large-scale implementation of this technique met with a great deal of resistance from most surgeons, and more surprisingly, from many breast radiologists in academia.

HOUSTON--Urinary incontinence is a common complication of cancer and cancer therapies that can impose long-term effects on quality of life; yet, this condition remains underemphasized in this patient population, Dorothy Smith, RN, OCN, director of Clinic Relations, Des Chutes Medical, Bend, Oregon, said at M.D. Anderson’s 2nd annual nursing conference.

NEW ORLEANS--A test based on the newly developed monoclonal antibody NMP179 can detect both low-grade and high-grade cervical dysplasia, according to results presented at the 89th annual meeting of the American Association for Cancer Research. The developers believe the test might one day be used as a supplement to the Pap smear.

This paper will address various issues relevant to core-needle biopsy of the breast under stereotactic imaging guidance. Patient and equipment selection, indications, contraindications, complications, limitations, and advantages will be discussed. The role of stereotactic core biopsy in patient management will also be addressed.

ROCKVILLE, Md--Without taking a formal vote, the FDA’s Biological Response Modifiers Advisory Committee (BRMAC) indicated its support for the approval of a label expansion for CellPro’s Ceprate SC System.

The American Association for Cancer Research (AACR) has named its officers and directors for 1998-1999. Webster K. Cavenee, PhD, will serve as AACR president for 1998-1999 with Daniel D. Von Hoff, MD, assuming the role of President-

BETHESDA, Md--Recruiting people from minority groups into clinical cancer trials calls for the biomedical community to be "compassionate, credible, and truthful" in how it portrays the value of those trials, Otis W. Brawley, MD, of the NCI’s Office of Special Populations Research, said at the American Society of Preventive Oncology annual meeting. "Physicians and medical institutions must have a good relationship with the people they serve," he said.

Early in the human immunodeficiency virus (HIV) epidemic, infection occurred disproportionately among older persons as a result of transmission through receipt of contaminated blood or blood products. Through 1989, receipt of contaminated

ARLINGTON, Va--When Arizona Oncology Associates (AOA), a 25-member group, "walked away" from a "bad" contract with a major local managed care organization (MCO), the practice prospered and the "majority of the patients we were caring for found ways to stay with us," Robert J. Brooks, MD, a medical oncologist in the group, said at the 24th Annual National Meeting of the Association of Community Cancer Centers (ACCC).

Helping Hand: The Resource Guide for People with Cancer, published by Cancer Care, Inc., is designed to “show what kinds of help are available, and where to find that help.” The second edition of A Helping Hand was recently released with updated listings, new sections (eg, using the Internet to find resources), and a myriad of information on national, regional, and local cancer-related organizations that provide important services for people with cancer. Included in the listings of A Helping Hand are the names of support groups, as well as medical information about a specific type of cancer, a second opinion, financial assistance, or hospice care.

NEW ORLEANS--Nutrition is a vital component of cancer management, yet nutritional assessment is still a very inexact science, Abby S. Bloch, PhD, RD, said at the 4th International Symposium on Nutrition and Cancer, sponsored by the Cancer Treatment Research Foundation and the Society for Nutritional Oncology Adjuvant Therapy.

A clinical pathway for pain management, developed by a task force of 18 registered nurses from Fox Chase Cancer Center and its network of community hospitals, was published in the January/February issue of Oncology Issues, the official journal

BETHESDA, Md--Over the next decade, Americans should put more effort into eating better and instituting chemoprevention trials to reduce cancer risks, said Peter Greenwald, MD, DrPH, acting director of the NCI’s Division of Cancer Prevention.