Management of Relapsed/Refractory Multiple Myeloma with Bispecifics: MonumenTAL-2, MajesTEC-1, and MagnetisMM-3 trials

Panelists discuss recent updates in the management of relapsed/refractory multiple myeloma, focusing on key studies such as MonumenTAL-2 for talquetamab, long-term follow-up data from the phase 1/2 MajesTEC-1 for teclistamab, and findings from MagnetisMM-3 regarding elranatamab.

EP: 1.Current Landscape of Relapsed/ Refractory Multiple Myeloma

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EP: 2.Management of Relapsed/Refractory Multiple Myeloma with Bispecifics: MonumenTAL-2, MajesTEC-1, and MagnetisMM-3 trials

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Comment on the recent updates surrounding the management of R/R MM with bispecifics and bispecific combination therapies:

• MonumenTAL-2 for talquetamab (Schinke CD et al. ASCO 2023 Abstract 8036)
• Long-term follow-up from the phase 1/2 MajesTEC-1 for teclistamab (Garfall et al. ASCO 2024 Abstract 7540)
• MagnetisMM-3for elranatamab in R/R MM (Lesokhin A, Nature 2023)

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