In this March 2016 news roundup we highlight two new FDA indications, chemotherapy’s long-term effect on fertility, the link between BMI and thyroid cancer, and more.
IDE397 Shows Preliminary Efficacy in MTAP+ NSCLC and Urothelial Cancer
Phase 1 expansion data may support potential combination development for IDE397 in NSCLC and urothelial cancer harboring MTAP deletions.
Empowering Awareness to Address Rising Gynecological Cancer Incidence
Ginger J. Gardner, MD, FACOG, highlights disease prevention innovations and other ongoing efforts to empower education in the gynecologic cancer field.
Mitigating Adverse Effects Following GPRC5DTargeted Therapy in Multiple Myeloma
A panel of experts in multiple myeloma discussed strategies for monitoring and mitigating adverse effects associated with GPRC5D-targeting bispecific agents.
Leveraging Ex Vivo Gene Therapy Advancements in Hemoglobinopathies and Metabolic Diseases
A panel of expert pharmacists provides their perspectives on gene therapy agents such as exagamglogene autotemcel in the management of sickle cell disease.
Evaluating Immunotherapy Options Based on Mutations for NSCLC
Experts discussed the efficacy and durability of immunotherapy responses in patients with NSCLC.
DLL3-Targeted ADC Produces Responses in Previously Treated ES-SCLC
Promising phase 1 data appear to support further evaluation of ZL-1310 as a treatment for patients with extensive-stage small cell lung cancer.