Medical professionals discuss factors influencing the decision between observation and treatment, optimal diagnostic methods for chronic lymphocytic leukemia (CLL), and key markers to assess in patients with suspected CLL.
Galinpepimut-S Completes Phase 3 REGAL Interim Analysis in AML
Interim phase 3 results revealed a median survival of at least 13.5 months with galinpepimut-S vs 6 months with standard of care in acute myeloid leukemia.
Managing Cytokine Release Syndrome in Patients on CAR T-Cell Therapy
Ahead of the ASCO Annual Meeting, we discuss the assessment and management of cytokine release syndrome in patients with cancer with Elizabeth Shpall, MD.
Chinese Study Finds Uproleselan/Chemo Does Not Meet OS End Point in R/R AML
Uproleselan plus chemotherapy did not demonstrate clinical benefit over chemotherapy alone, though did show an acceptable safety profile.
Immunotherapy Approaches in AML
Cancer Network sat down with Dr. Naval Daver to discuss advancements and discoveries in immunotherapy for AML patients.
Obe-cel Elicits Durable Responses in Relapsed/Refractory B-Cell ALL
In the phase 1b/2 FELIX study, obecabtagene autoleucel was associated with low incidence of grade 3 or higher immune-related toxicity.
Bezuclastinib Demonstrates Improved Symptoms in Systemic Mastocytosis
Median duration on bezuclastinib was 56 weeks vs 40 weeks for placebo in non-advanced systemic mastocytosis, the phase 2 Summit trial reported.