Cover Story Barrie Cassileth, an integrative medicine pioneer Move to make CME an out-of-pocket cost gains ground Will presidential candidates’ promises to cancer research be enough? DEPARTMENTS Focus on Colon Cancer Calcium-magnesium is neuroprotective in patients receiving oxaliplatin Vantage Point: Intermittent schedule not yet widely adopted News & Analysis Melanoma: Can future therapies improve prognosis? Focus on Breast Cancer Some HER2+ tumors prove resistant to trastuzumab Molecular breast imaging detects mammographically occult cancers International News Nanoparticles extend survival in pancreatic ca patients