Additional Data Reported for Ongoing Phase I/II AUTO3 Clinical Trials Treating DLBCL
February 4th 2020The data was presented at the EHA-EBMT 2nd European CAR T-Cell Meeting, which took place on January 30, 2020 in Barcelona, Spain, and showed encouraging signs of a manageable safety profile in adults with relapsed/refractory DLBCL.
Phase I Trial Aims to Evaluate Cobomarsen in Certain Hematologic Malignancies
February 4th 2020The phase I trial is evaluating cobomarsen in cancers where the disease process appears to be correlated with an increase in miR-155 levels, including adult T-cell leukemia/lymphoma, diffuse large B-cell lymphoma, and chronic lymphocytic leukemia.
Different Strategies May Be Necessary for Single Hormone Receptor-Positive Breast Cancer
February 3rd 2020This suggestion is based on statistically significant distinctions observed in survival rates of patients with single hormone receptor-positive breast cancer vs double hormone receptor-positive/double hormone receptor-negative breast cancer.
Phase III ARAMIS Trial Showed Significant Improvement in OS for Patients with Prostate Cancer
January 31st 2020The investigation of darolutamide plus ADT in men with non-metastatic castration-resistant prostate cancer indicated a significant improvement in overall survival in this patient population.
Improved Long-Term QOL Observed for Pediatric Cancer Survivors as Treatments Evolve
January 30th 2020Regardless of these improvements though, researchers noted that cancer survivors remain at risk for shorter lifespans, particularly when radiotherapy was utilized as a part of their childhood cancer treatment.
Varying Overall Survival Indicated Depending on Institution for Patients with HNC
January 30th 2020Patients with head and neck cancer saw better overall survival when treated at academic comprehensive cancer programs and integrated network cancer programs, compared to comprehensive community cancer programs and community cancer programs.
Inaccurate Risk Perceptions Lead to Worry and Decreased QOL in Patients with Thyroid Cancer
January 29th 2020The perceptions, which were associated with worry and a decreased quality of life, indicated the need for patient education that is suitable for diverse populations and improved risk communication by physicians.
Genentech Submits sBLA for Atezolizumab Plus Bevacizumab Combo to Treat Unresectable HCC
January 27th 2020The company’s application is based on results from the phase III IMbrave150 study of the regimen for the treatment of patients with unresectable hepatocellular carcinoma who have not received prior systemic therapy.
Health Insurance Coverage May Mediate Racial/Ethnic Disparities in Late-Stage Breast Cancer
January 25th 2020Researchers noted that these findings do not indicate that insurance alone will eliminate racial and ethnic disparities in breast cancer; however, it is one systemic change that may ameliorate consistent disparities.
AI System Possibly Capable of Surpassing Human Experts in Breast Cancer Prediction
January 24th 2020Researchers have yet to determine the optimal use of the AI system, though assessments in the clinical setting indicated that the technology could enhance screening results, potentially identifying breast cancer earlier than the standard of care.