Auto-SCT or CAR T? A Case-Based Discussion in Relapsed DLBCL

Opinion
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Panelists discuss how the choice between chimeric antigen receptor T-cell (CAR T) therapy and autologous stem cell transplantation (auto-SCT) requires careful evaluation of multiple patient-specific factors. Medical professionals consider disease type and stage, prior treatments, patient age and fitness, cytogenetic risk, donor availability, and timing. CAR T may be preferred for relapsed/refractory cases, whereas transplant remains standard for eligible newly diagnosed patients.

Video content above is prompted by the following:

  • How do the factors of CAR T vs transplant considerations​ influence your decision-making in different patient scenarios?​
  • What factors would guide your choice between auto-SCT vs CAR T therapy?

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