Jason’s Journey with ALK+ Metatstatic NSCLC

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This is an actor portrayal of a hypothetical patient profile developed for educational purposes based on characteristics of patients with ALK+ non-small cell lung cancer as seen in clinical practice. The hypothetical case was co-developed by staff Medical Writers with Cancer Network/ONN.

  • 34-year-old professional rock climber with ALK+ Stage IV metastatic NSCLC, previously healthy with no smoking history.
  • Persistent lower back pain unresponsive to rest and PT, followed by increased fatigue led to initial doctor visit.
  • CT scan revealed a left lung mass with lymph node involvement and a small metastasis on the spine; molecular testing confirmed ALK-positive status.
  • Started on lorlatinib, with manageable GI issues and fatigue as side effects; patient is motivated to return to climbing.
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