Social Media Recruiting for Trials Falls Short
A survey of physicians found recruiting for trials through social media can be useful, but not for cancer therapeutic trials.
Novel Combination Treatment for Differentiated Thyroid Cancer
Researchers look at how mutation status can influence responses to targeted therapy in thyroid cancer.
Pembrolizumab and PFS in Advanced Melanoma
Researchers report on the best pembrolizumab protocol for advanced melanoma.
Sentinel Node Biopsy in Clinical Stage I Testicular Cancer
Investigators report on long-term results of sentinel node (SN) approach in patients with clinical stage I testicular tumors.
Study Finds High Number of European Cancer Drug Trials at Risk for Bias
Half of the cancer drug trials that led to approvals by the European Medicines Agency may have been associated with a high risk for bias.
FDA Grants Breakthrough Therapy Designation to Niraparib for mCRPC
The agency granted breakthrough therapy designation to niraparib for the treatment of men with BRCA1/2-mutant positive metastatic castration-resistant prostate cancer.
Role of COX7RP in Endometrial, Breast Cancer Growth
COX7RP contributes to endometrial and breast cancer growth.
Three-Drug Palliative Chemotherapy Regimen Shows Promise for Advanced Oral Cancer
The methotrexate-based regimen proved to lengthen survival and improve quality of life among patients with platinum-resistant oral cancer.
PD-L1 Inhibition Plus Pegilodecakin Active in Advanced Solid Tumor All-Comers
A combination of pegilodecakin (pegylated IL-10) with an anti-PD-L1 monoclonal antibody inhibitor showed preliminary antitumor activity.
Prognostic Value of Intraoperative Bile Spillage in Gallbladder Adenocarcinoma
Intraoperative bile spillage might serve as a prognostic tool for gall bladder cancer.
Analysis of Cervical Mutations Aids Endometrial Cancer Diagnosis
Diagnosis of endometrial carcinoma made easier by analysis of mutations in cervix or endometrial tissue.
Oncologists Responsive to FDA Label Restrictions
After the FDA restricted the labels of 2 drugs used to treat bladder cancer, oncologists' use of these treatments decreased drastically.
Unexpected Uterine Cancer: Power Morcellation and Mortality
Coffee and Pancreatic Cancer Risk Among Never-Smokers
Researchers believe that previous findings about coffee consumption’s possible link to an increased risk of pancreatic cancer come from confounding factors that were not accounted for, such as smoking.
Germline Investigation in Male Breast Cancer
Although rare, is breast cancer in males genetic? Researchers provide details.
Incidence of Non-Melanoma Skin Cancer Tallies Biggest Change From 2016 to 2017
The Global Burden of Disease 2017 study found non-melanoma skin cancer to be the biggest increase in incidence worldwide.
FDA Approves Darzalex Combo as Frontline Treatment for Myeloma
The combination use of Darzalex with bortezomib, thalidomide, and dexamethasone was approved for transplant-eligible patients with multiple myeloma.
What Percentage of Cancer Diagnoses Are Made in the Emergency Department?
Some patients are more likely to find out about their cancer via a visit to the emergency department than others.
FDA Expands Indicated Age Range for CRC Screening Tool
As more younger adults are diagnosed with colorectal cancer, the FDA approved Cologuard, a stool-based, at-home colorectal cancer screening, for adults aged 45 to 49 years.
Tibolone's Role in Glioblastoma
Investigators assessed effects of TIB on cell number, migration, invasion, estrogen, and progesterone receptor activity and content.
Effect of Antibiotics on Immunotherapy Outcomes ‘Urgently Requires’ Further Look
Administration of antibiotics prior to immune checkpoint inhibitor therapy may reduce response to treatment and worsen survival outcomes in patients with cancer.
Role of EPS8L3 Upregulation in Liver Cancer
Researchers recently reported on the association between upregulation of EPS8L3 and liver cancer prognosis.
Symptom Burden High Among Survivors Years After Diagnosis
Researchers examined whether cancer or treatment type impacted the symptom burden of survivors of cancer.
Can Recurrent Ovarian Cancer Patients Avoid Chemotherapy?
The AVANOVA2 trial enrolled a total of 97 patients with high-grade serous or endometrioid platinum-sensitive recurrent ovarian cancer.
Clinical Trials in Breast and Endometrial Cancer
Many clinical trials in breast and endometrial cancers are underway and recruiting patients.
Therapy Options for Patients With Hepatocellular Carcinoma
Therapy options for patients with hepatocellular carcinoma (HCC), including a newly approved therapy for a subpopulation of patient.
Project Orbis Enables First International Approval in U.S., Canada, Australia
The first-of-its-kind collaboration led to the approval of a combination therapy for patients with endometrial cancer.
Health Savings Accounts Linked to Care Access in Cancer Survivors
Whether a cancer survivor had a health savings account (HSA) as part of their high-deductible health plan was linked to access to care.
FDA Approves Apalutamide for Prostate Cancer
Apalutamide was initially approved in 2018 for patients with non-metastatic castration-resistant prostate cancer; the recent approval is for patients with metastatic castration-sensitive prostate cancer.
Adolescents and Young Adults with Cancer Report Sexual Dissatisfaction
There's been much research done on how cancer of the reproductive organs affects patients' sexuality; this new study included patients with cancers outside the reproductive organs.